Psilocybin vs SSRI: Long-Term Well-Being Compared

Psilocybin vs SSRI for depression: Psilocybin vs SSRI: Long-Term Well-Being Compared

In a six-month follow-up of a small phase 2 randomized controlled trial, adults with moderate to severe depression who received psilocybin therapy showed greater improvements in work and social functioning, meaning in life, and connectedness than those who received the SSRI escitalopram, though both groups reduced depressive symptom scores at similar levels. Key takeaways Comparable […]

Psilocybin and Brain Entropy: Changes Lasting One Month

Psilocybin brain entropy: Psilocybin and Brain Entropy: Changes Lasting One Month

In a small controlled study of 28 healthy adults, a single 25 mg dose of psilocybin increased brain entropy during the experience, and participants reported greater psychological insight and improved well-being up to one month later. Structural imaging also showed changes in neural tract integrity. These are early findings in a healthy, non-clinical sample. Key […]