A news segment from New York explored the possibility that psilocybin, the compound found in certain mushrooms, could serve as an alternative or complement to opioid prescriptions. The underlying science remains early-stage, and no clinical consensus exists yet on psilocybin as an addiction treatment. Key takeaways The conversation is active in New York: Journalists and […]
A single dose of psilocybin appears to reduce reward-seeking behavior in rats for at least 48 hours after administration, and a new study published in the European Journal of Neuroscience now points to a specific cellular mechanism that may explain why: the increased activation of inhibitory neurons wrapped in specialized structures called perineuronal nets. The […]
A study published in JAMA reports that psilocybin shows promise as a treatment for cocaine use disorder. This finding is notable because it extends the growing addiction-related evidence base for psilocybin beyond the substances most commonly studied, namely alcohol and tobacco, into a stimulant dependency that has long proven difficult to treat. What the Research […]
A study published in May 2026 in a peer-reviewed journal indexed on PubMed reports that psilocybin reduced preference for large rewards in rats, and that this behavioral shift was accompanied by increased activity of a specific class of neurons in the dorsomedial prefrontal cortex. The findings offer a candidate neurological mechanism for one of psilocybin’s […]