Mental Health
Depression, anxiety, integration, and the inner work — how psilocybin meets the mind, told through both clinical evidence and human experience.
Never Miss What Matters
One weekly email. The best psilocybin research, podcasts, and news from trusted sources around the world — no searching required.
Psilocybin for Opioid Alternatives: What We Know So Far
A news segment from New York explored the possibility that psilocybin, the compound found in certain mushrooms, could serve as an alternative or complement to opioid prescriptions. The…
Psilocybin’s Neural Effects: What Brain Research Shows
Psilocybin, the active compound in certain fungi, primarily acts on serotonin receptors in the brain. Research suggests it disrupts ordinary patterns of neural communication and may increase connectivity…
Psilocybin for Chronic Pain: A Rehabilitation Framework
A 2025 focus article published in the Journal of Pain proposes that psilocybin could act as a “psychophysical adaptogen” in chronic pain rehabilitation, potentially loosening what the authors…
Psilocybin as an Anti-Aging Compound: What the Early Science Suggests
Psilocybin has spent the last decade earning its place in the conversation around depression, anxiety, and end-of-life distress. Now, according to reporting from VICE, researchers are beginning to…
Healing Is Relational: A Case for Systemic Psilocybin Therapy
Most psilocybin research treats healing as something that happens inside one person. A new conceptual article published in Psychedelic Medicine challenges that assumption directly, proposing that the relationships…
Psilocybin Reshapes How Neural Networks Talk to Each Other
A new study reports that psilocybin changes the way the brain communicates internally, with findings pointing specifically to altered connectivity across neural networks. While the source text does…
One Dose, Lasting Quiet: Psilocybin Dims Reward-Seeking Through Inhibitory Brain Cells
A single dose of psilocybin appears to reduce reward-seeking behavior in rats for at least 48 hours after administration, and a new study published in the European Journal…
Psilocybin as Antidepressant: What the Research Actually Says
Psilocybin, the active compound in so-called magic mushrooms, is attracting serious scientific and clinical interest as a possible alternative to conventional antidepressants. Canadian publication Maclean’s has joined a…
Can Psychedelics Protect the Aging Brain?
Researchers at the University of California, Berkeley are investigating whether psychedelic compounds may offer neuroprotective benefits for the aging brain, with a focus on mechanisms that could be…
One Dose, Weeks of Relief: Psilocybin and Brain Network Restructuring
A single dose of psilocybin appears capable of producing sustained relief from depression by restructuring how brain networks communicate with one another. According to reporting by Medical News…
You've Come This Far. Stay Informed.
Join our free weekly newsletter and get the best psilocybin research, medical journals, podcasts, and news — hand-curated from trusted sources around the world and delivered straight to your inbox.