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Mental Health

Depression, anxiety, integration, and the inner work — how psilocybin meets the mind, told through both clinical evidence and human experience.

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Psilocybin and anxiety mechanism: Resetting the hippocampal buffer: a neurocognitive account of psychedelic therapy for anxiety-related psychopathology
Mental Health

Psilocybin and Anxiety: A Hippocampal Reset Theory

A theoretical paper published in Psychopharmacology in 2026 proposes that anxiety disorders may involve a kind of stuck pattern in the hippocampus, a brain structure central to memory…

Psilocybin traumatic brain injury: Psilocybin for Traumatic Brain Injury: What a Narrative Review Found
Mental Health

Psilocybin for Traumatic Brain Injury: What a Narrative Review Found

A narrative review indexed on NIH platforms examined the possible mechanisms by which psilocybin could support recovery from traumatic brain injury, focusing on neuroplasticity pathways. The review is…

Psychedelic use among veterans: Psychedelic Use Among Veterans: What a RAND Study Found
Mental Health

Psychedelic Use Among Veterans: What a RAND Study Found

A 2026 RAND survey study estimates that approximately 4.8 million U.S. veterans have used psilocybin mushrooms, LSD, or MDMA. About half of those veterans reported uncertainty about whether…

Psychedelic support line: Fireside Project's Lucy: AI Training for Psychedelic Support
Mental Health

Fireside Project’s Lucy: AI Training for Psychedelic Support

Fireside Project, a nonprofit psychedelic support line, has handled more than 30,000 calls since launching in April 2021. The organization recently introduced Lucy, a voice-based AI role-play simulator…

Psilocybin and SSRIs: what the interaction means for you
Mental Health

Psilocybin and SSRIs: what the interaction means for you

Physician Tracy Townsend produced a video addressing whether psilocybin can be safely used alongside SSRIs, a class of antidepressants taken by roughly one in eight American adults. The…

Psilocybin opioid alternative: Psilocybin for Opioid Alternatives: What We Know So Far
Mental Health

Psilocybin for Opioid Alternatives: What We Know So Far

A news segment from New York explored the possibility that psilocybin, the compound found in certain mushrooms, could serve as an alternative or complement to opioid prescriptions. The…

What psilocybin does to the brain: Psilocybin's Neural Effects: What Brain Research Shows
Mental Health

Psilocybin’s Neural Effects: What Brain Research Shows

Psilocybin, the active compound in certain fungi, primarily acts on serotonin receptors in the brain. Research suggests it disrupts ordinary patterns of neural communication and may increase connectivity…

Psilocybin for Chronic Pain: A Rehabilitation Framework
Mental Health

Psilocybin for Chronic Pain: A Rehabilitation Framework

A 2025 focus article published in the Journal of Pain proposes that psilocybin could act as a “psychophysical adaptogen” in chronic pain rehabilitation, potentially loosening what the authors…

Psilocybin anti-aging: Psilocybin as an Anti-Aging Compound: What the Early Science Suggests - The Church of Psychedelics
Mental Health

Psilocybin as an Anti-Aging Compound: What the Early Science Suggests

Psilocybin has spent the last decade earning its place in the conversation around depression, anxiety, and end-of-life distress. Now, according to reporting from VICE, researchers are beginning to…

Suggested Guidelines for Applying a Systemic Lens to Psychedelic-Assisted Psychotherapy.
Mental Health

Healing Is Relational: A Case for Systemic Psilocybin Therapy

Most psilocybin research treats healing as something that happens inside one person. A new conceptual article published in Psychedelic Medicine challenges that assumption directly, proposing that the relationships…

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