Clinical Trials
Peer-reviewed studies, trial results, and the science as it lands — what the latest psilocybin research actually found, read plainly and without the hype.
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Psilocybin and Aging: What a New Review Found
A 2024 review paper by Mark Haden and colleagues, published in a peer-reviewed outlet and summarized by Drug Science, argues that psilocybin and other psychedelics may affect multiple…
Psilocybin Approval: FDA Hears Debate on Access and Safety
On September 14, 2026, the FDA held a public hearing to gather input on how psychedelic medicines should be used after approval. Speakers disagreed sharply on provider qualifications,…
Psilocybin for Depression in Health Care Workers: Early Signal
A University of Utah report, published in late October 2025, describes preliminary research into psilocybin as a possible intervention for depression among health care workers. Full methodology and…
Psilocybin for Migraine: What Early Studies Found
In a small pilot trial of 10 adults with migraine, participants reported fewer attacks and less severe pain during the two weeks following low-dose oral psilocybin. A separate…
Psilocybin for Depression: What the Research Actually Shows
In a 24-person Johns Hopkins study, antidepressant effects from psilocybin combined with supportive psychotherapy lasted at least a year in some patients with moderate to severe major depressive…
Psilocybin for Treatment-Resistant Depression: Mechanism Review
In a commentary published on PubMed Central, researchers reviewed two clinical trials suggesting that a single 25 mg dose of psilocybin may produce rapid antidepressant effects in treatment-resistant…
Psilocybin for Fibromyalgia: Safety in a Small Pilot
In a small open-label pilot of five adults with fibromyalgia, psilocybin-assisted therapy was reported to be safe and well tolerated, with no serious adverse events. Several participants showed…
Psilocybin for Veterans’ PTSD: Majority Reach Remission
A clinical study examined psilocybin-assisted therapy in veterans diagnosed with PTSD and found that the majority of participants reached symptom remission. The findings are early-stage and require replication,…
Psilocybin for Advanced Cancer: Inside a National Trial
In an ongoing randomized clinical trial, researchers at the University of Colorado and New York University are studying whether a single 25-milligram dose of synthetic psilocybin, paired with…
Psilocybin for Cancer Distress: Colorado Trial Launches
Colorado-based researchers have launched, or are preparing to launch, a clinical trial examining whether psilocybin-assisted therapy can reduce anxiety and depression in cancer patients. Details about sample size,…
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