Psilocybin Significantly Aids Smoking Cessation in New Clinical Study

Psilocybin smoking cessation: Psilocybin Significantly Aids Smoking Cessation in New Clinical Study - The Church of Psychedelics

A new clinical study has found that psilocybin significantly aids smoking cessation, offering some of the clearest evidence yet that psychedelic-assisted treatment may have a meaningful role in helping people break free from nicotine addiction. The findings, reported by NPR, add important weight to a field that has been steadily building its case over the […]

Psilocybin Extends Cellular Lifespan by Over 50%, New Emory Study Finds

Psilocybin longevity research: Psilocybin Extends Cellular Lifespan by Over 50%, New Emory Study Finds - The Church of Psychedelics

A study published July 8, 2025 in npj Aging reports that psilocin, the compound your body produces when it metabolizes psilocybin, extended the lifespan of human skin and lung cells by more than 50% in laboratory conditions and improved the survival rate of elderly mice by 30% over a ten-month treatment period. The research was […]

Healing Is Relational: A Case for Systemic Psilocybin Therapy

Suggested Guidelines for Applying a Systemic Lens to Psychedelic-Assisted Psychotherapy.

Most psilocybin research treats healing as something that happens inside one person. A new conceptual article published in Psychedelic Medicine challenges that assumption directly, proposing that the relationships surrounding a person may be just as important to lasting recovery as the medicine itself. Written by Sara N. Lappan and Sean D. Davis of Alliant International […]

Psilocybin Reshapes How Neural Networks Talk to Each Other

Psilocybin brain connectivity: Psilocybin Reshapes How Neural Networks Talk to Each Other - The Church of Psychedelics

A new study reports that psilocybin changes the way the brain communicates internally, with findings pointing specifically to altered connectivity across neural networks. While the source text does not detail the study’s size, methodology, or the exact networks involved, the core finding is that the compound appears to reorganize, at least temporarily, the patterns through […]

One Dose, Lasting Quiet: Psilocybin Dims Reward-Seeking Through Inhibitory Brain Cells

Psilocybin reduces reward-seeking behavior: One Dose, Lasting Quiet: Psilocybin Dims Reward-Seeking Through Inhibitory Brain Cells - The Church of Psychedelics

A single dose of psilocybin appears to reduce reward-seeking behavior in rats for at least 48 hours after administration, and a new study published in the European Journal of Neuroscience now points to a specific cellular mechanism that may explain why: the increased activation of inhibitory neurons wrapped in specialized structures called perineuronal nets. The […]

Psilocybin Eases Sleep and May Reshape Brain Structure in Chronic Cluster Headache

Psilocybin cluster headache sleep: Psilocybin Eases Sleep and May Reshape Brain Structure in Chronic Cluster Headache - The Church of Psychedelics

A study published in May 2026 reports that psilocybin significantly improved sleep quality in patients living with chronic cluster headache, one of the most debilitating pain conditions known to medicine. The research also observed trends toward changes in white matter microstructure as measured by diffusion-weighted MRI, a finding that is preliminary but points toward a […]

Australia’s First Psilocybin Trial Targets Persistent Concussion Symptoms

Psilocybin trial for concussion symptoms: Australia's First Psilocybin Trial Targets Persistent Concussion Symptoms - The Church of Psychedelics

Up to half of all people who sustain a concussion will carry its effects long after the initial injury fades, living with headaches, dizziness, cognitive fog, irritability, and disrupted sleep that can persist for months or years. There are few proven therapies for this condition, and many patients are left managing symptoms without meaningful relief. […]

Psilocybin as Antidepressant: What the Research Actually Says

Psilocybin as Antidepressant: What the Research Actually Says - The Church of Psychedelics

Psilocybin, the active compound in so-called magic mushrooms, is attracting serious scientific and clinical interest as a possible alternative to conventional antidepressants. Canadian publication Maclean’s has joined a growing number of mainstream outlets examining whether this long-stigmatized substance could have a meaningful role in treating depression, one of the most prevalent and difficult-to-treat conditions in […]

USC Secures Funding for First Clinical Study of Psilocybin for Mental Health

Psilocybin mental health clinical study: USC Secures Funding for First Clinical Study of Psilocybin for Mental Health - The Church of Psychedelics

Researchers at the University of Southern California have secured funding to initiate what is being described as the first clinical study of psilocybin specifically focused on mental health. The announcement marks a meaningful institutional step, moving psilocybin research from preliminary inquiry into the structured world of formal clinical investigation. What the Funding Means for Psilocybin […]

What Six Trials Now Tell Us About Psilocybin for Depression

Psilocybin for depression: What Six Trials Now Tell Us About Psilocybin for Depression - The Church of Psychedelics

A systematic review and meta-analysis published in the Journal of Affective Disorders by researchers at Fujita Health University and Keio University School of Medicine has pooled data from six randomized controlled trials to assess how psilocybin therapy performs against control conditions in treating major depressive disorder (MDD), tracking both efficacy and safety across multiple time […]